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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1545 | D-Tyrosine | Tyrosinase | |
D-Tyrosine, the D-isomer of tyrosine, acts as a negative regulator of melanin synthesis by inhibiting tyrosinase activity. Furthermore, D-Tyrosine also inhibits biofilm formation and induces the self-dispersal of biofilm... | |||
T39275 | Befotertinib | D-0316,Befotertinib | EGFR |
Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cell lung cancer. | |||
T8636 | Ibrutinib deacryloylpiperidine | IBT4A,5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine | BTK |
Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM. | |||
TN1053 | Aloe-emodin-8-O-β-D-glucopyranoside | Aloe-emodin-8-O-beta-D-glucopyranoside | Phosphatase |
Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro. | |||
T10190 | 7-BIA | Phosphatase | |
7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties and can be used in the study of neuropathic pain. | |||
T4511 | ST271 | ST 271 | Phospholipase , Tyrosine Kinases |
ST271 is an effective protein tyrosine kinase (PTK) inhibitor. | |||
T4518 | Licochalcone D | ERK , NF-κB | |
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect... | |||
T9543 | Syk Inhibitor II hydrochloride | Others | |
The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of... | |||
T5290 | (S)-2-Hydroxy-3-phenylpropanoic acid | L-(−)-3-Phenyllactic acid | Others , Endogenous Metabolite |
(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase. The ... | |||
T75501 | Morin 3-O-β-D-glucopyranoside | ||
Morin 3-O-β-D-glucopyranoside, a natural flavonoid, exhibits antifungal, anticancer, and antioxidant properties. This compound also inhibits reverse transcriptase, protein-tyrosine kinase, and xanthine oxidase, while dem... | |||
T75495 | Rubrofusarin 6-O-β-D-glucopyranoside | ||
Rubrofusarin 6-O-β-D-glucopyranoside, a glycosidic derivative of Rubrofusarin, functions as an inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 87.36 μM. It is utilized in research investigating... | |||
T3827 | Rhein-8-glucoside calcium | Rhein-8-O-β-D-glucopyranoside,Rhein-8-glucoside calcium salt | Phosphatase , Antibacterial |
Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium (Rhein-8-glucoside calcium salt) salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro. | |||
T37079 | VEGFR2 Kinase Inhibitor II | ||
Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms... | |||
T36367 | RK-682 (calcium salt) | ||
Protein tyrosine phosphatases (PTPs) remove phosphate from tyrosine residues of cellular proteins. Reversible phosphorylation catalyzed by the coordinated actions of protein tyrosine kinases and phosphatases is key to th... | |||
T36384 | DL-Tyrosine-13C9,15N | L-Tyrosine-13C9,15N | |
L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylal... | |||
T68389 | LY2457546 | ||
LY2457546 is a potent and orally bioavailable inhibitor of multiple receptor tyrosine kinases involved in angiogenic and tumorigenic signalling. LY2457546 demonstrates potent activity against targets that include VEGFR2 ... | |||
T35583 | Hirudin (54-65; non-sulfated) (trifluoroacetate salt) | ||
Hirudin (54-65; non-sulfated) is a desulfated peptide fragment of hirudin, an anticoagulant produced byH. medicinalis.1It inhibits fibrin clot formation induced by isolated bovine thrombin with an IC50value of 3.7 μM.2 1... | |||
T36648 | Tucatinib hemiethanolate | ||
Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-f... | |||
T36643 | PKI-166 hydrochloride | ||
Potent EGFR-kinase inhibitor (IC50 = 0.7 nM). Displays >3000-fold selectivity against a panel of serine/threonine kinases. Reduces metastasis and angiogenesis in a mouse model of pancreatic cancer. Antihypertensive and o... |